Company 41 (Wrightsville), 21 (Hellam), and Truck 8-1 (Columbia) sent to 108 Hellam Street "Hometown Hotel" for a structure fire with entrapment. Chief officer from Co. 41 on location with heavy fire on the second floor extending to the third floor. Fire building was a 3 story, mixed occupancy (apartments over a bar) with exposures on the B and D side. The fire went 2nd alarm immediately bringing in companies from both York and Lancaster Counties to the scene. Companies performed searches and fire suppression for almost a half hour before evacuation the structure and going to master streams. The fire was placed under control two hours after going 4 alarms. One occupant and a firefighter were transported for injuries and approximately 20 people were left homeless. The fire is believed to be a case of arson, set by a resident.